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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Cinnamic acid, Ethacrynic acid
Phytochemical Name Cinnamic acid (PubChem CID: 444539 )
Anticancer drug Name Ethacrynic acid (PubChem CID: 3278 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 340
Pair Name Cinnamic acid, Ethacrynic acid
Disease Info [ICD-11: 2B33.2] Chronic myeloid leukemia Investigative
Biological Phenomena Induction-->Blockade of cell cycle in G2/M phase
In Vitro Model K-562 Blast phase chronic myelogenous leukemia Homo sapiens (Human) CVCL_0004
Result Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells
03. Reference
No. Title Href
1 Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells. Mol Biol Rep. 2022 Aug;49(8):7521-7530. doi: 10.1007/s11033-022-07560-5. Click
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